Gary Ruvkun, Ph.D.
Massachusetts Institute of Technology

Exploration of the C.elegans insulin-like aging pathway.

Dr. Ruvkun has previously shown that an insulin-like signaling pathway regulates longevity and metabolism in C. elegans. The most important output of this pathway in C. elegans is the transcription factor DAF-16. Dr. Ruvkun now proposes to search for the downstream targets of DAF-16 in order to identify the downstream daf-16 genes involved in longevity control.

Contact Dr. Ruvkun.