Funded Institutions

Institutions with funded Senior Scholars: Albert Einstein College of Medicine of Yeshiva University Baylor College of Medicine Brandeis University Buck Institute for Age Research Burnham Institute California Institute of Technology Children's Hospital, Boston Children's Hospital, Harvard Medical School Children's Hospital, Oakland Research Institute Cornell University Emory University Fred Hutchinson Cancer Research Center Harvard Medical School Johns Hopkins School of Public Health Johns Hopkins University School of Medicine Lawrence Berkeley National Laboratory Massachusetts Institute of Technology Molecular Sciences Institute Scripps Research Institute Skirball Institute - New York University School of Medicine Stanford University School of Medicine Stanford University School of Medicine, VA Palo Alto Health Care System The Rockefeller University University of California Los Angeles University of California, Irvine University of California, San Diego, Howard Hughes Medical Institute University of California, San Francisco University of California, San Francisco, UCSF Cancer Center University of Chicago University of Colorado at Boulder University of Connecticut Health Center University of Idaho University of Kentucky University of North Carolina at Chapel Hill University of Southern California University of Texas, Southwest Medical Center University of Washington Weill Medical College of Cornell University Whitehead Institute for Biomedical Research Yale University School of Medicine Yale University School of Medicine, Howard Hughes Medical Institute

Institutions with funded New Scholars: Albert Einstein College of Medicine of Yeshiva University Baylor College of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School Brigham and Women's Hospital Harvard Medical School Brown University California Institute of Technology Cold Spring Harbor Laboratory Colorado State University Cornell University Dana Farber Cancer Institute, Harvard Medical School Duke University Medical Center Fox Chase Cancer Center Harvard Medical School Massachusetts General Hospital Massachusetts Institute of Technology Mayo Clinic, Jacksonville National Institute of Neurological Disorders and Stroke, National Institutes of Health National Institute on Aging, National Institutes of Health National Jewish Medical Center Scripps Research Institute Skirball Institute - New York University School of Medicine St. Jude Children’s Research Hospital, Memphis The Rockefeller University Tufts University School of Medicine University of Alabama at Birmingham University of California at Santa Cruz University of Connecticut Health Center University of Iowa University of Kentucky Chandler Medical Center University of Minnesota Cancer Center University of North Carolina at Chapel Hill University of Rochester Medical Center University of Texas, Southwest Medical Center University of Washington School of Medicine University. of Texas Medical School at Houston Vanderbilt University School of Medicine Yale University School of Medicine

Funded Scholars

Senior Scholar Awards - 1998

Seymour Benzer,  Ph.D. California Institute of Technology Life extension genes in Drosophila	Judith Campisi,  Ph.D. Lawrence Berkeley National Laboratory Telomeres, Cell Phenotype and Aging	Luca Cavalli-Sforza,  M.D. Stanford University School of Medicine Genes Controlling Longevity in Centenarians
Stephen J. Elledge,  Ph.D. Baylor College of Medicine Connections Between the Telomere Sensing and DNA Damage Accumulation	Daniel E. Gottschling,  Ph.D. Fred Hutchinson Cancer Research Center Replicative senescence in S. cerevisia	Paul Greengard,  Ph.D. The Rockefeller University Novel APP - containing synaptic organelles and Alzheimer's disease
Carol W. Greider,  Ph.D. Johns Hopkins University School of Medicine The Roles of Recombination and Telomerase in Telomere Maintenance	Leonard Guarente,  Ph.D. Massachusetts Institute of Technology Molecular analysis of mammalian aging	Thomas E. Johnson,  Ph.D. University of Colorado at Boulder Identification of gerontogenes in the mouse
Cynthia J. Kenyon,  Ph.D. University of California, San Francisco Analysis of genes that control aging in C. elegans	Louis M. Kunkel,  Ph.D. Children's Hospital, Harvard Medical School Exploring the genetics of extreme longevity	Gregory A. Petsko,  D. Phil. Brandeis University How cells die in Alzheimer's and other neurodegenerative diseases
Gary Ruvkun,  Ph.D. Massachusetts Institute of Technology Exploration of the C.elegans insulin-like aging pathway	Jerry W Shay,  Ph.D. University of Texas, Southwest Medical Center Role of telomeres and telomerase in human aging

Senior Scholar Awards - 1999

Bruce N. Ames,  Ph.D. Children's Hospital, Oakland Research Institute Reversal of Mitochondrial Decay: From Rats to Humans	Steven N. Austad,  Ph.D. University of Idaho Genetic Mechanisms of Exceptional Oxidative Damage Resistance in Birds	James E. Cleaver,  Ph.D. University of California, San Francisco, UCSF Cancer Center Endogenous DNA Damage and Mechanisms of Aging
Gretchen J. Darlington,  Ph.D. Baylor College of Medicine Identification of Candidate Genes for Longevity in Long Lived Mouse Models	Titia de Lange,  M.D. , Ph.D. The Rockefeller University The Role of T-loops in Aging of Human Cells	Michael E. Greenberg,  Ph.D. Children's Hospital, Boston The Role of P13K/Akt Dependent Phosphorylation of a Mammalian Fork Head Transcription Factor FKHRL1 in Cell Senescence and Organismal Aging
Lawrence A. Loeb,  M.D., Ph.D. University of Washington Aging in Mutator and Antimutator Mice	David S. Thaler,  Ph.D. The Rockefeller University Mitochondrial Mutation and Aging	Douglas C. Wallace,  Ph.D. Emory University Mitochondrial Aging in the Chimpanzee
Sherman M. Weissman,  M.D. Yale University School of Medicine The Molecular/Physiological Basis for Accelerated Aging in the Werner's Syndrome

Senior Scholar Awards - 2000

Giuseppe Attardi,  M.D. California Institute of Technology Aging-dependent Large Accumulation of Mutations at Specific Sites in Human Mitochondrial DNA Control Region	Tamas Bartfai,  Ph. D. Scripps Research Institute Chronic Neuroprotection during Aging by UCP Mediated Simultaneous Reduction of Free Radical Formation and Exocitotoxicity	Nir Barzilai,  M.D. Albert Einstein College of Medicine of Yeshiva University Identification of Longevity Genes in Founder Populations
Roger Brent,  Ph. D. Molecular Sciences Institute Identification of Protein Regulators of Self-renewal, Differentiation, and Senescence in Embryonic Stem Cells	Linda B. Buck,  Ph. D. Harvard Medical School A High Throughput Screen for Longevity Genes	Jack D. Griffith,  Ph. D. University of North Carolina at Chapel Hill Telomere Looping and Control of Cell Aging
Philip C. Hanawalt,  Ph. D. Stanford University School of Medicine Repair of Oxidative DNA Damage in Human Neurons	Peter J. Hornsby,  Ph. D. Baylor College of Medicine Cell Transplantation Models for Gene Action in Human Aging	Thomas Kornberg,  Ph. D. University of California, San Francisco Toward a Comprehensive Assessment of Gene Expression during Development and Aging of Drosophila
Charles M. Lieber,  Ph. D. Harvard Medical School Molecular through Cellular Changes Responsible for Alzheimer's Disease	David Ron,  Ph. D. Skirball Institute - New York University School of Medicine Proteotoxicity and Aging	Thomas P. Sakmar,  M.D. The Rockefeller University The Chromophore Regeneration Pathway in Age-related Macular Degeneration
Sangram S. Sisodia,  Ph. D. University of Chicago Molecular Determinants of Hippocampal Neuroplasticity in a Mouse Model of b-Amyloid Deposition

Senior Scholar Awards in Aging - 2001

Helen M. Blau,  Ph.D. Stanford University School of Medicine Bone Marrow to Brain: Searching for markers of bone marrow stem cells with neurogenic potential	Jochen Buck,  M.D., Ph.D. Weill Medical College of Cornell University Bicarbonate-activated adenylyl cyclase and aging	Catherine F. Clarke,  Ph.D., co-PI University of California Los Angeles Intersection of two pathways in control of aging: nutritional coenzyme Q and DAF-2 signaling
Lawrence S.B. Goldstein,  Ph.D. University of California, San Diego, Howard Hughes Medical Institute Probing the role of axonal transport disturbance and transport-mediated signaling in Alzheimer’s Disease	Stephen Helfand,  M.D. University of Connecticut Health Center Genetic Dissection of Aging in Drosophila	Pamela L. Larsen,  Ph.D., co-PI University of California Los Angeles Intersection of two pathways in control of aging: nutritional coenzyme Q and DAF-2 signaling
Stuart Lipton,  M.D., Ph.D. Burnham Institute Use of Blood Stem Cells to Regenerate Neurons via the Transcription Factor hMEF2C	Victoria Lundblad,  Ph.D. Baylor College of Medicine Translating Yeast Telomere Biology to Human Cells: Identification of Activities that Regulate Human Telomere Maintenance and Cellular Proliferation	Mark Mayford,  Ph.D. Scripps Research Institute Mutagenic Screen for Longevity Genes in Mice
Simon Melov,  Ph.D. Buck Institute for Age Research Critically Testing the Free Radical Theory of Aging, and Development of a Practical Intervention	Fernando Nottebohm,  Ph.D. The Rockefeller University Hypothesis to be tested: some aspects of functional aging result from reduced replacement in the adult CNS	John Tower,  Ph.D. University of Southern California Replicative Senescence of Drosophila Stem Cells in Vivo
Phyllis M. Wise,  Ph.D. University of Kentucky Estradiol is a Neuroprotective Factor in the Aging Brain: Mechanisms of Action

Senior Scholar Awards in Global Infectious Disease - 2001

Alan G. Barbour,  M.D. University of California, Irvine Transmission-blocking Vaccines Against Arthropod Vectors	William Bishai,  M.D., Ph.D. Johns Hopkins School of Public Health Transmission Blocking Vaccines for Tuberculosis	Jon Clardy,  Ph.D. Cornell University New Antibiotics from Environmental DNA
Peter Cresswell,  Ph.D. Yale University School of Medicine, Howard Hughes Medical Institute Antiviral Effects of Interferon-Inducible Cytosolic Proteins	Stanley Falkow,  Ph.D. Stanford University School of Medicine The Natural History of Typhoid Infection in Vietnam	Gerald R. Fink,  Ph.D. Whitehead Institute for Biomedical Research The Role of Quorum Sensing in Fungal Disease
Lee Gehrke,  Ph.D. Massachusetts Institute of Technology Exploiting an Evolutionary Omission in Pathogenic RNA Viruses: Understanding the Advantages of BeingNon-polyadenylated	William R. Jacobs, Jr.,  Ph.D. Albert Einstein College of Medicine of Yeshiva University Development of Genetic Systems for Genetically Intractable Organisms	Keith A. Joiner,  M.D., co-PI Yale University School of Medicine Development of New Genetic Tools to Identify Nutrient Uptake Pathways in Malaria Parasites
W. Ian Lipkin,  M.D. University of California, Irvine Pandora’s Box Project	Richard M. Locksley,  M.D. University of California, San Francisco Optimizing Immunity to Complex Pathogens In Vivo	David A. Relman,  M.D. Stanford University School of Medicine, VA Palo Alto Health Care System The Human Intestinal Microbiome: Community Analysis, Host Response, and Role in Chronic Disease
Iwona Stroynowski,  Ph.D. University of Texas, Southwest Medical Center Exploring Novel Pathways of Immune Defenses Against Orally Ingested Pathogens: Analysis of Nonclassical Class I MHC Antigens in Mouse Intestines	Elisabetta Ullu,  Ph.D., co-PI Yale University School of Medicine Development of New Genetic Tools to Identify Nutrient Uptake Pathways in Malaria Parasites

New Scholar Awards - 1998

Phillip A. Cole,  M.D., Ph.D The Rockefeller University Inhibition of N-acetyltransferase	Todd Golde,  M.D., Ph.D Mayo Clinic, Jacksonville Presenilins and Gamma-Secretase Cleavage of the Amyloid Beta Protein Precursor	Francine Grodstein,  Sc.D. Brigham and Women's Hospital Harvard Medical School Estrogen, Antioxidants, and Cognitive Function in Women
Bruce Hay,  Ph.D. California Institute of Technology Apoptosis	Elly Nedivi,  Ph.D. Massachusetts Institute of Technology CPG15, A Novel Growth Promoting Molecule Involved in Synaptic Plasticity	Hong Yan,  Ph.D. Brigham and Women's Hospital Harvard Medical School Identification of Proteins Functionally Redundant to the Werner's Syndrome Gene Product

New Scholar Awards - 1999

Dominique Broccoli,  Ph.D. Fox Chase Cancer Center Molecular Mechanisms of Telomere Dependent Senescence	Phillip Carpenter,  Ph.D. University. of Texas Medical School at Houston Biochemical Characterization of a Putative p53-binding Protein from Xenopus	Stewart Frankel,  Ph.D. Yale University School of Medicine The Regulation of Chromosomes and Longevity
Shiv L. S. Grewal,  Ph.D. Cold Spring Harbor Laboratory Heterochromatin Assembly and Replicative Life-Span in Fission Yeast	Danesh Moazed,  Ph.D. Harvard Medical School Connections Between the Nucleolus and Cellular Aging	Henry L. Paulson,  M.D., Ph.D. University of Iowa Mechanisms of Neuronal Dysfunction and Death in Neurodegenerative Proteinpathies
Zhou Songyang,  Ph.D. Baylor College of Medicine Functional Analysis of Aging and Cell Survival Signal Pathways in Mammalian Cells	David Q.H. Wang,  M.D., Ph.D. Beth Israel Deaconess Medical Center, Harvard Medical School Aging and Cholesterol Gallstone Formation: Molecular Mechanisms of Gallstone (Lith) Genes	Weidong Wang,  Ph.D. National Institute on Aging, National Institutes of Health Characterization of a Novel Protein Complex Involved in the Human Premature Aging Disease - Werner Syndrome
Huaxi Xu,  Ph.D. The Rockefeller University Gonadal Steroid Regulation of ß-Amyloid Generation: Cellular Mechanisms and Animal Models

New Scholar Awards - 2000

Jay M. Edelberg,  Ph. D. Cornell University Regulation of Senescent Angiogenic Potential	Jeffrey S. Friedman,  Ph. D. Dana Farber Cancer Institute, Harvard Medical School The Role of p66shc in Cellular Senescence and Mammalian Aging	Wen-Biao Gan,  Ph. D. Skirball Institute - New York University School of Medicine In Vivo Study of Age-related Changes in Synaptic Structure
Mike Hutton,  Ph. D. Mayo Clinic, Jacksonville In Vivo Analysis of the Role of Tau in Neurodegeneration.	David K. Orren,  Ph. D. University of Kentucky Chandler Medical Center Understanding the Role of Genomic Instability in Human Aging: The Paradigm of the Premature Aging Disease Werner Syndrome	Jeff J. Sekelsky,  Ph. D. University of North Carolina at Chapel Hill Functional Characterization of a Drosophila RecQ Helicase
Hong-Bing Shu,  Ph. D. National Jewish Medical Center Signaling by Tumor Necrosis Factor Family Members	James E. Sligh,  M.D., Ph. D. Vanderbilt University School of Medicine Altered Mitochondrial Function in Transgenic Models of Cutaneous Aging	Peiqing Sun,  Ph. D. Scripps Research Institute A Genetic Approach to Identification of Genes Involved in Cellular Senescence and Immortalization
Marc Tatar,  Ph. D. Brown University Neuroendocrine Regulation of Aging in Drosophila	Anthony D. Wagner,  Ph. D. Massachusetts Institute of Technology Age-related Changes in the Functional Neurobiology of Memory	Hui Zheng,  Ph. D. Baylor College of Medicine An Inducible Gene Knockout System for Alzheimer's Disease and Aging Research

New Scholar Awards in Aging- 2001

Michael J. Bertram,  Ph.D. University of Alabama at Birmingham Genetic Analysis of the MORF4 Related Gene Family in Drosophila: Insights into Cellular Senescence	Sandy Chang,  M.D.,Ph.D Dana Farber Cancer Institute, Harvard Medical School Genomic Instability and Aging in Werner-Telomerase Compound Knockout Mice	Michael D. Ehlers,  M.D., Ph.D. Duke University Medical Center Molecular Mechanisms of Age-Related Changes at Hippocampal Synapses
Roman Giger,  Ph.D. University of Rochester Medical Center Mechanisms of Neural Plasticity in the Mammalian System	Yasunori Hayashi,  M.D., Ph.D. Massachusetts Institute of Technology Role of Neural Progenitors in Adult Hippocampal- and Olfactory Bulb-Dependent Learning and Memory	Kyung-Tai Min,  Ph.D. National Institute of Neurological Disorders and Stroke, National Institutes of Health Life Extension of Drospohila by a Drug Treatment
William A. Mohler,  Ph.D. University of Connecticut Health Center New Approaches to Characterizing Cellular Changes in Sarcopenia	Robert Sheaff,  Ph.D. University of Minnesota Cancer Center A Mechanistic Explanation for the Development of Neurodegenerative Diseases	David A. Sinclair,  Ph.D. Harvard Medical School Identification of Genes and Compounds that Extend Yeast Life Span
David G. Wells,  Ph.D. Yale University School of Medicine Synaptic Plasticity in the Aging Brain: Role of CPE-dependent Protein Synthesis

New Scholar Awards in Global Infectious Disease 2001

David A. Fidock,  Ph.D. Albert Einstein College of Medicine of Yeshiva University Genetic Determinants of Chloroquine Resistance in Plasmodium falciparum Malaria	Michael Gale Jr.,  Ph.D. University of Texas, Southwest Medical Center Mechanisms of Hepatitis C Virus Persistence	Claudia Häse,  Ph.D. St. Jude Children’s Research Hospital, Memphis Identification of the Bioenergetics Sensor Affecting Virulence Factor statement in Vibrio cholerae
John D. McKinney,  Ph.D. The Rockefeller University Genetic Analysis of TB Persistence: Identification of New Drug Targets	Karen M. Ottemann,  Ph.D. University of California at Santa Cruz Helicobacter pylori: Proteins and Processes that Contribute to Persistent Infection	Lalita Ramakrishnan,  M.D., Ph.D. University of Washington School of Medicine Bacterial and Host Contributions to the Maintenance of the Granuloma in Tuberculosis Infections
Joseph D. Smith,  Ph.D. Colorado State University Genome-wide Binding Analysis of the Plasmodium falciparum Erythrocyte Membrane 1 Family of Cytoadherent Receptors	Jatin M. Vyas,  M.D., Ph.D. Massachusetts General Hospital Antigen Processing and Presentation in the Specialized Enterocyte, M Cell	Paula Watnick,  M.D., Ph.D. Tufts University School of Medicine Novel Regulators of Biofilm Development by Vibrio cholerae
Elizabeth Winzeler,  Ph.D. Scripps Research Institute Functional Analysis of the Plasmodium Genome

Infrastructure Award

Kenneth Paigen, Ph. D. The Jackson Laboratory, Genetic Resources Building.	Ellis Rubenstein, Ph. D. American Association for the Advancement of Science, Science of Aging Knowledge Environment. (SAGE KE)	Sherrilynne Fuller, Ph.D. University of Washington , Telemachus Knowledge Discovery in Aging Resource
Luca Cavalli-Sforza, M.D. Stanford University School of Medicine , Human Genome Diversity Project-Centre d'Etude du Polymorphisme Humain Initiative	Mark Smolinski, M.D., M.P.H. The National Academies Institute of Medicine, Emerging Microbial Threats to Health in the 21st Century	Gerald Weissmann, M.D. New York University School of Medicine The Undeveloped Drug
Robert Hay, Ph.D. and Ray Cypress, D.V.M., Ph.D Developmental Biology Resource Center American Type Culture Collection (ATCC)

Conferences and Workshops - 1998

Thomas Kirkwood, Ph.D. The Gordon Conferences, University of Rhode Island, Gordon Research Conference on the Biology of Aging, Barga, Italy.

Shuguang Zhang Massachusetts Institute of Technology, A multidisciplinary workshop: Self-assembling peptide systems in biology, engineering and medicine.

Conferences and Workshops - 1999

S. Michal Jazwinski, Ph.D. The Gordon Conferences, University of Rhode Island, Gordon Research Conference on the Biology of Aging, Ventura, CA	Robert Arking, Ph.D. Gerontological Society of America, Washington, DC, GSA Biological Sciences Meeting, San Francisco, CA.	Vilhelm Bohr, M.D., Ph.D., D.Sc. National Institute on Aging, GRC, Baltimore, FASEB Conference on Molecular Gerontology, Copper Mountain, CO
Donald K. Ingram, Ph.D. American Aging Association, American Aging Association (AGE) 28th Annual Meeting, Seattle, WA

Conferences and Workshops - 2000

John B. Macauley, Ph.D. The Jackson Laboratory, 3rd Genectics of Aging Meeting

Caleb E. Finch, Ph.D. Ethel Percy Andrus Gerontology Center, University of Southern California Symposium on Organisms with Slow Aging

Robert Butler, M.D., International Longevity Center Biomarkers of Aging: From Rodents to Man

Conferences and Workshops - 2001

Douglas R. Green, Ph.D. 2001 Keystone Symposia Molecular Mechanisms of Apoptosis	Steven W. Matson, Ph.D. Federation of American Societies for Experimental Biology, FASEB Summer Research Conference	James F. Nelson, Ph.D. and Phyllis M Wise, Ph.D. The Gordon Research Conferences, University of Rhode Island Gordon Research Conference on the Biology of Aging
Jonathan Davis, Ph.D. The National Academies Institute of Medicine Consequences of Disease Eradication	Jonathan Davis, Ph.D. The National Academies Institute of Medicine Chronic Diseases and Emerging Infections	Bruce Alberts, Ph.D. National Academy of Sciences 2001 - 2003 U.S. Frontiers of Science Symposium
Helen Blau, Ph.D. Stanford University School of Medicine Aging: Biology, Disease, and Economics	Dan Bergstralh The University of North Carolina at Chapel Hill Molecular Mechanisms of Aging and Senescence	Shugang Zhang, Ph.D. Massachusetts Institute of Technology Second Multidisciplinary Workshop: Self-assembling Peptide Systems in Biology, Engineering and Medicine
Terry Pellmar, Ph.D. National Academy of Sciences Therapeutic Potential of Stem Cell Research	Michael E. Greenberg, Ph.D. The Gordon Research Conferences, University ofRhode Island Gordon Research Conference on NeurotrophicFactors